Journal: Integrative Medicine Research
Article Title: Ameliorative effects of Wiryeongtang (herbal medicine) on cardiorenal complications via modulation of inflammatory and fibrotic responses in diabetic mice
doi: 10.1016/j.imr.2026.101322
Figure Lengend Snippet: The effects of WRT on renal morphology changes in db/db mice . (A) Kidney type and (B) Right/left kidney weight change. (C) Representative periodic acid-Schiff (PAS) staining of kidney section (5 mm, Magnification: 40×, scale bars:100 μm) and (D) Glomerular surface area and mesangial surface area. (E) Urinary KIM-1 measurement for indication of tubular injury. db/m, non-diabetic control mice; db/db, diabetic mice (untreated); vilda, vildagliptin-treated mice (positive control; db/db + vildagliptin); WRT, Wiryeongtang-treated mice (db/db + WRT). Data are expressed as mean±SD (n=5). **p<0.01 vs db/m group; #p<0.05, ##p<0.01 vs db/db group.
Article Snippet: Serum insulin (Shibyagi Co., Gunma, Japan) and KIM-1 (LSBIO., Ltd., Ishihara Shibukawa, Gunma, Japan) levels were measured using ELISA kits.
Techniques: Staining, Control, Positive Control